Selective targeting p53WT lung cancer cells harboring homozygous p53 Arg72 by an inhibitor of CypA-Reference-Cited by-同舟云学术

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Selective targeting p53WT lung cancer cells harboring homozygous p53 Arg72 by an inhibitor of CypA

Published:2017-04-10 Issue:33 Volume:36 Page:4719-4731
ISSN:0950-9232
Container-title:Oncogene
language:en
Short-container-title:Oncogene

Author:

Lu W,Cheng F,Yan W,Li X,Yao X,Song W,Liu M,Shen X,Jiang H,Chen J,Li J,Huang J

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Genetics,Molecular Biology

Link

http://www.nature.com/articles/onc201741.pdf

Reference44 articles.

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2. Cohen P, Alessi DR . Kinase drug discovery—what's next in the field? ACS Chem Biol 2012; 8: 96–104.

3. Crystal AS, Shaw AT, Sequist LV, Friboulet L, Niederst MJ, Lockerman EL et al. Patient-derived models of acquired resistance can identify effective drug combinations for cancer. Science 2014; 346: 1480–1486.

4. Knight ZA, Lin H, Shokat KM . Targeting the cancer kinome through polypharmacology. Nat Rev Cancer 2010; 10: 130–137.

5. Bai JP, Abernethy DR . Systems pharmacology to predict drug toxicity: integration across levels of biological organization. Annu Rev Pharmacol Toxicol 2013; 53: 451–473.

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