Long-read sequencing unveils IGH-DUX4 translocation into the silenced IGH allele in B-cell acute lymphoblastic leukemia-Reference-Cited by-同舟云学术

Long-read sequencing unveils IGH-DUX4 translocation into the silenced IGH allele in B-cell acute lymphoblastic leukemia

Published:2019-06-26 Issue:1 Volume:10 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Tian Liqing^ORCID,Shao Ying,Nance Stephanie,Dang Jinjun,Xu Beisi^ORCID,Ma Xiaotu,Li Yongjin,Ju Bensheng,Dong Li,Newman Scott^ORCID,Zhou Xin,Schreiner Patrick,Tseng Elizabeth,Hon Ting,Ashby Meredith,Li Chunliang,Easton John,Gruber Tanja A.,Zhang Jinghui^ORCID

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/s41467-019-10637-8.pdf

Reference49 articles.

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2. Perlot, T. & Alt, F. W. Cis-regulatory elements and epigenetic changes control genomic rearrangements of the IgH locus. Adv. Immunol. 99, 1–32 (2008).

3. Vettermann, C. & Schlissel, M. S. Allelic exclusion of immunoglobulin genes: models and mechanisms. Immunol. Rev. 237, 22–42 (2010).

4. Proudhon, C., Hao, B., Raviram, R., Chaumeil, J. & Skok, J. A. Long-range regulation of V(D)J recombination. Adv. Immunol. 128, 123–182 (2015).

5. Russell, L. J. et al. IGH@ translocations are prevalent in teenagers and young adults with acute lymphoblastic leukemia and are associated with a poor outcome. J. Clin. Oncol. 32, 1453–1462 (2014).

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