Flow-sensory contact electrification of graphene

Author:

Zhang XiaoyuORCID,Chia EricORCID,Fan Xiao,Ping JingleiORCID

Abstract

AbstractAll-electronic interrogation of biofluid flow velocity by electrical nanosensors incorporated in ultra-low-power or self-sustained systems offers the promise of enabling multifarious emerging research and applications. However, existing nano-based electrical flow sensing technologies remain lacking in precision and stability and are typically only applicable to simple aqueous solutions or liquid/gas dual-phase mixtures, making them unsuitable for monitoring low-flow (~micrometer/second) yet important characteristics of continuous biofluids (such as hemorheological behaviors in microcirculation). Here, we show that monolayer-graphene single microelectrodes harvesting charge from continuous aqueous flow provide an effective flow sensing strategy that delivers key performance metrics orders of magnitude higher than other electrical approaches. In particular, over six-months stability and sub-micrometer/second resolution in real-time quantification of whole-blood flows with multiscale amplitude-temporal characteristics are obtained in a microfluidic chip.

Funder

United States Department of Defense | United States Air Force | AFMC | Air Force Office of Scientific Research

United States Department of Defense | United States Army | Army Medical Command | Congressionally Directed Medical Research Programs

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

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