Non-coding variability at the APOE locus contributes to the Alzheimer’s risk
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Link
http://www.nature.com/articles/s41467-019-10945-z.pdf
Reference72 articles.
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3. Saunders, A. M. et al. Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease. Neurology 43, 1467–1472 (1993).
4. Strittmatter, W. J. et al. Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc. Natl Acad. Sci. USA 90, 1977–1981 (1993).
5. Bullido, M. J. et al. A polymorphism in the regulatory region of APOE associated with risk for Alzheimer's dementia. Nat. Genet 18, 69–71 (1998).
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