Myopathy associated BAG3 mutations lead to protein aggregation by stalling Hsp70 networks-Reference-Cited by-同舟云学术

Myopathy associated BAG3 mutations lead to protein aggregation by stalling Hsp70 networks

Published:2018-12 Issue:1 Volume:9 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Meister-Broekema Melanie,Freilich Rebecca,Jagadeesan Chandhuru,Rauch Jennifer N.,Bengoechea Rocio,Motley William W.,Kuiper E. F. Elsiena,Minoia Melania,Furtado Gabriel V.,van Waarde Maria A. W. H.,Bird Shawn J.,Rebelo Adriana,Zuchner Stephan,Pytel Peter,Scherer Steven S.,Morelli Federica F.,Carra Serena,Weihl Conrad C.,Bergink Steven,Gestwicki Jason E.^ORCID,Kampinga Harm H.

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/s41467-018-07718-5.pdf

Reference52 articles.

1. Stürner, E. & Behl, C. The role of the multifunctional BAG3 protein in cellular protein quality control and in disease. Front. Mol. Neurosci. 10, 177 (2017).

2. Xu, Z. et al. 14-3-3 protein targets misfolded chaperone-associated proteins to aggresomes. J. Cell Sci. 126, 4173–4186 (2013).

3. Jia, B., Wu, Y. & Zhou, Y. 14-3-3 and aggresome formation: implications in neurodegenerative diseases. Prion 8, 173–177 (2014).

4. Carra, S., Seguin, S. J., Lambert, H. & Landry, J. HspB8 chaperone activity toward poly(Q)-containing proteins depends on its association with Bag3, a stimulator of macroautophagy. J. Biol. Chem. 283, 1437–1444 (2008).

5. Kampinga, H. H. & Bergink, S. Heat shock proteins as potential targets for protective strategies in neurodegeneration. Lancet Neurol. 15, 748–759 (2016)

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