Restricted cell cycle is essential for clonal evolution and therapeutic resistance of pre-leukemic stem cells
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Link
http://www.nature.com/articles/s41467-018-06021-7.pdf
Reference58 articles.
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3. Mullighan, C. G. et al. Genomic analysis of the clonal origins of relapsed acute lymphoblastic leukemia. Science 322, 1377–1380 (2008).
4. Sykes, S. M., Kokkaliaris, K. D., Milsom, M. D., Levine, R. L. & Majeti, R. Clonal evolution of preleukemic hematopoietic stem cells in acute myeloid leukemia. Exp. Hematol. 43, 989–992 (2015).
5. Klco, J. M. et al. Association between mutation clearance after induction therapy and outcomes in acute myeloid leukemia. JAMA 314, 811–822 (2015).
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