Structural and functional consequences of the STAT5BN642H driver mutation-Reference-Cited by-同舟云学术

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Structural and functional consequences of the STAT5BN642H driver mutation

Published:2019-06-07 Issue:1 Volume:10 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

de Araujo Elvin D.^ORCID,Erdogan Fettah^ORCID,Neubauer Heidi A.,Meneksedag-Erol Deniz^ORCID,Manaswiyoungkul Pimyupa,Eram Mohammad S.,Seo Hyuk-Soo^ORCID,Qadree Abdul K.,Israelian Johan^ORCID,Orlova Anna,Suske Tobias,Pham Ha T. T.^ORCID,Boersma Auke,Tangermann Simone,Kenner Lukas,Rülicke Thomas^ORCID,Dong Aiping,Ravichandran Manimekalai,Brown Peter J.^ORCID,Audette Gerald F.^ORCID,Rauscher Sarah^ORCID,Dhe-Paganon Sirano,Moriggl Richard^ORCID,Gunning Patrick T.

Funder

Austrian Science Fund

Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada

Gouvernement du Canada | Canadian Institutes of Health Research

Canada Research Chairs

Canadian Cancer Society Research Institute

Canadian Breast Cancer Foundation

Canada Foundation for Innovation

Ontario Research Foundation

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/s41467-019-10422-7.pdf

Reference77 articles.

1. Stark, G. R. & Darnell, J. E. The JAK-STAT pathway at twenty. Immunity 36, 503–514 (2012).

2. Hennighausen, L. & Robinson, G. W. Interpretation of cytokine signaling through the transcription factors STAT5A and STAT5B. Genes Dev. 22, 711–721 (2008).

3. Reich, N. C. STATs get their move on. JAK-STAT 2, e27080 (2013).

4. Schwartzman, O. et al. Suppressors and activators of JAK-STAT signaling at diagnosis and relapse of acute lymphoblastic leukemia in Down syndrome. Proc. Natl Acad. Sci. 114, E4030–E4039 (2017).

5. Pham, H. T. T. et al. STAT5BN642H is a driver mutation for T cell neoplasia. J. Clin. Invest. 128, 387–401 (2018).

Cited by 56 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The structural influence of the oncogenic driver mutation N642H in the STAT5B SH2 domain;2024-09-10

2. Morphology, immunophenotype, and suggested diagnostic criteria of TCL1 family–negative T-prolymphocytic leukemia;American Journal of Clinical Pathology;2024-06-30

3. A lineage-specific STAT5BN642H mouse model to study NK-cell leukemia;Blood;2024-06-13

4. Perinatal thymic-derived CD8αβ-expressing γδ T cells are innate IFN-γ producers that expand in IL-7R–STAT5B-driven neoplasms;Nature Immunology;2024-05-27

5. Hyperactive STAT5 hijacks T cell receptor signaling and drives immature T cell acute lymphoblastic leukemia;Journal of Clinical Investigation;2024-04-15

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