Mapping eGFR loci to the renal transcriptome and phenome in the VA Million Veteran Program

Author:

Hellwege Jacklyn N.ORCID,Velez Edwards Digna R.,Giri AyushORCID,Qiu Chengxiang,Park JihwanORCID,Torstenson Eric S.,Keaton Jacob M.,Wilson O. D.,Robinson-Cohen Cassianne,Chung Cecilia P.,Roumie Christianne L.,Klarin DerekORCID,Damrauer Scott M.,DuVall Scott L.ORCID,Siew Edward,Akwo Elvis A.,Wuttke MatthiasORCID,Gorski MathiasORCID,Li ManORCID,Li YongORCID,Gaziano J. Michael,Wilson Peter W. F.,Tsao Philip S.,O’Donnell Christopher J.,Kovesdy Csaba P.,Pattaro CristianORCID,Köttgen AnnaORCID,Susztak KatalinORCID,Edwards Todd L.ORCID,Hung Adriana M.ORCID

Funder

U.S. Department of Health & Human Services | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development

U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases

Deutsche Forschungsgemeinschaft

Else Kröner-Fresenius-Stiftung

U.S. Department of Veterans Affairs

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Reference94 articles.

1. Levey, A. S. & Coresh, J. Chronic kidney disease. Lancet 379, 165–180 (2012).

2. Go, A. S., Chertow, G. M., Fan, D., McCulloch, C. E. & Hsu, C. Y. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N. Engl. J. Med. 351, 1296–1305 (2004).

3. Tonelli, M. et al. Risk of coronary events in people with chronic kidney disease compared with those with diabetes: a population-level cohort study. Lancet 380, 807–814 (2012).

4. System, U. S. R. D. USRDS Annual Data Report: Epidemiology of Kidney Disease in the United States. (National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, 2017).

5. Prevention, C.f.D.C.a. National Chronic Kidney Disease Fact Sheet. (US Department of Health and Human Services, Centers for Disease Control and Prevention, Atlanta, GA, 2017).

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