A conformational switch in initiation factor 2 controls the fidelity of translation initiation in bacteria
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Link
http://www.nature.com/articles/s41467-017-01492-6.pdf
Reference40 articles.
1. Tsai, A. et al. Heterogeneous pathways and timing of factor departure during translation initiation. Nature 487, 390–393 (2012).
2. Milón, P., Maracci, C., Filonava, L., Gualerzi, C. O. & Rodnina, M. V. Real-time assembly landscape of bacterial 30S translation initiation complex. Nat. Struct. Mol. Biol. 19, 609–615 (2012).
3. Hartz, D., McPheeters, D. S. & Gold, L. Selection of the initiator tRNA by Escherichia coli initiation factors. Genes Dev. 3, 1899–1912 (1989).
4. Antoun, A., Pavlov, M. Y., Lovmar, M. & Ehrenberg, M. How initiation factors tune the rate of initiation of protein synthesis in bacteria. EMBO J. 25, 2539–2550 (2006).
5. Antoun, A., Pavlov, M. Y., Lovmar, M. & Ehrenberg, M. How initiation factors maximize the accuracy of tRNA selection in initiation of bacterial protein synthesis. Mol. Cell 23, 183–193 (2006).
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