Multiplexed in vivo homology-directed repair and tumor barcoding enables parallel quantification of Kras variant oncogenicity-Reference-Cited by-同舟云学术

Multiplexed in vivo homology-directed repair and tumor barcoding enables parallel quantification of Kras variant oncogenicity

Published:2017-12 Issue:1 Volume:8 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Winters Ian P.^ORCID,Chiou Shin-Heng,Paulk Nicole K.^ORCID,McFarland Christopher D.,Lalgudi Pranav V.^ORCID,Ma Rosanna K.^ORCID,Lisowski Leszek^ORCID,Connolly Andrew J.,Petrov Dmitri A.^ORCID,Kay Mark A.,Winslow Monte M.^ORCID

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/s41467-017-01519-y.pdf

Reference80 articles.

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3. Gillet, J. P., Varma, S. & Gottesman, M. M. The clinical relevance of cancer cell lines. J. Natl Cancer Inst. 105, 452–458 (2013).

4. Kersten, K., De Visser, K. E., Van Miltenburg, M. H. & Jonkers, J. Genetically engineered mouse models in oncology research and cancer medicine. EMBO Mol. Med. https://doi.org/10.15252/emmm.201606857 (2016).

5. Zehir, A. et al. Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients. Nat. Med. https://doi.org/10.1038/nm.4333 (2017).

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