Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels-Reference-Cited by-同舟云学术

Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels

Published:2018-06-13 Issue:1 Volume:9 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Zheng Wang,Yang Xiaoyong,Hu Ruikun,Cai Ruiqi,Hofmann Laura,Wang Zhifei,Hu Qiaolin,Liu Xiong,Bulkley David,Yu Yong,Tang Jingfeng,Flockerzi Veit,Cao Ying,Cao Erhu,Chen Xing-Zhen

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/s41467-018-04586-x.pdf

Reference70 articles.

1. Ong, A. C. & Harris, P. C. A polycystin-centric view of cyst formation and disease: the polycystins revisited. Kidney Int. 10, 699–710 (2015).

2. Gabow, P. A. Autosomal dominant polycystic kidney disease—more than a renal disease. Am. J. Kidney Dis. 16, 403–413 (1990).

3. Harris, P. C. & Torres, V. E. Polycystic kidney disease. Annu. Rev. Med. 60, 321–337 (2009).

4. Ramsey, I. S., Delling, M. & Clapham, D. E. An introduction to TRP channels. Annu. Rev. Physiol. 68, 619–647 (2006).

5. Arif, P. M. et al. Function and regulation of TRPP2 ion channel revealed by a gain-of-function mutant. Proc. Natl. Acad. Sci. USA 113, E2363–E2372 (2016).

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