ERK-mediated phosphorylation regulates SOX10 sumoylation and targets expression in mutant BRAF melanoma
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Link
http://www.nature.com/articles/s41467-017-02354-x.pdf
Reference39 articles.
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2. Sosman, J. A. et al. Survival in BRAF V600-mutant advanced melanoma treated with vemurafenib. New Engl. J. Med. 366, 707–714 (2012).
3. Flaherty, K. T. et al. Inhibition of mutated, activated BRAF in metastatic melanoma. New Engl. J. Med. 363, 809–819 (2010).
4. Chapman, P. B. et al. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. New Engl. J. Med. 364, 2507–2516 (2011).
5. Aplin, A. E., Kaplan, F. M. & Shao, Y. Mechanisms of resistance to RAF inhibitors in melanoma. J. Invest. Dermatol. 131, 1817–1820 (2011).
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