Synthetic TRuC receptors engaging the complete T cell receptor for potent anti-tumor response
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Link
http://www.nature.com/articles/s41467-019-10097-0.pdf
Reference51 articles.
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3. Maude, S. L., Teachey, D. T., Porter, D. L. & Grupp, S. A. CD19-targeted chimeric antigen receptor T-cell therapy for acute lymphoblastic leukemia. Blood 125, 4017–4023 (2015).
4. Locke, F. L. et al. Phase 1 results of ZUMA-1: a multicenter study of KTE-C19 anti-CD19 CAR T cell therapy in refractory aggressive lymphoma. Mol. Ther. 25, 285–295 (2017).
5. Schamel, W. W., Alarcon, B., Höfer, T. & Minguet, S. The allostery model of TCR regulation. J. Immunol. 198, 47–52 (2017).
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