Synthetic TRuC receptors engaging the complete T cell receptor for potent anti-tumor response-Reference-Cited by-同舟云学术

Synthetic TRuC receptors engaging the complete T cell receptor for potent anti-tumor response

Published:2019-05-07 Issue:1 Volume:10 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Baeuerle Patrick A.,Ding Jian,Patel Ekta,Thorausch Niko,Horton Holly,Gierut Jessica,Scarfo Irene^ORCID,Choudhary Rashmi,Kiner Olga,Krishnamurthy Janani,Le Bonnie,Morath Anna,Baldeviano G. Christian,Quinn Justin,Tavares Patrick,Wei Qi,Weiler Solly,Maus Marcela V.^ORCID,Getts Daniel,Schamel Wolfgang W.,Hofmeister Robert

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/s41467-019-10097-0.pdf

Reference51 articles.

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3. Maude, S. L., Teachey, D. T., Porter, D. L. & Grupp, S. A. CD19-targeted chimeric antigen receptor T-cell therapy for acute lymphoblastic leukemia. Blood 125, 4017–4023 (2015).

4. Locke, F. L. et al. Phase 1 results of ZUMA-1: a multicenter study of KTE-C19 anti-CD19 CAR T cell therapy in refractory aggressive lymphoma. Mol. Ther. 25, 285–295 (2017).

5. Schamel, W. W., Alarcon, B., Höfer, T. & Minguet, S. The allostery model of TCR regulation. J. Immunol. 198, 47–52 (2017).

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