Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Link
http://www.nature.com/articles/s41467-018-06649-5.pdf
Reference45 articles.
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3. Zhu, G. et al. A major quantitative-trait locus for mole density is linked to the familial melanoma gene CDKN2A: a maximum-likelihood combined linkage and association analysis in twins and their sibs. Am. J. Hum. Genet 65, 483–492 (1999).
4. Wachsmuth, R. C. et al. Heritability and gene-environment interactions for melanocytic nevus density examined in a U.K. adolescent twin study. J. Invest Dermatol. 117, 348–352 (2001).
5. Falchi, M. et al. Genome-wide association study identifies variants at 9p21 and 22q13 associated with development of cutaneous nevi. Nat. Genet. 41, 915–919 (2009).
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