SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4-Reference-Cited by-同舟云学术

SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4

Published:2018-12 Issue:1 Volume:9 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Tzelepis Konstantinos,De Braekeleer Etienne,Aspris Demetrios,Barbieri Isaia,Vijayabaskar M. S.,Liu Wen-Hsin,Gozdecka Malgorzata,Metzakopian Emmanouil,Toop Hamish D.^ORCID,Dudek Monika,Robson Samuel C.,Hermida-Prado Francisco,Yang Yu Hsuen,Babaei-Jadidi Roya,Garyfallos Dimitrios A.,Ponstingl Hannes^ORCID,Dias Joao M. L.^ORCID,Gallipoli Paolo^ORCID,Seiler Michael,Buonamici Silvia,Vick Binje^ORCID,Bannister Andrew J.,Rad Roland,Prinjha Rab K.^ORCID,Marioni John C.^ORCID,Huntly Brian^ORCID,Batson Jennifer^ORCID,Morris Jonathan C.^ORCID,Pina Cristina,Bradley Allan,Jeremias Irmela^ORCID,Bates David O.,Yusa Kosuke,Kouzarides Tony,Vassiliou George S.^ORCID

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/s41467-018-07620-0.pdf

Reference35 articles.

1. Ferrara, F. & Schiffer, C. A. Acute myeloid leukaemia in adults. Lancet 381, 484–495 (2013).

2. Tzelepis, K. et al. A CRISPR dropout screen identifies genetic vulnerabilities and therapeutic targets in acute myeloid leukemia. Cell Rep. 17, 1193–1205 (2016).

3. Lai, M. C., Lin, R. I. & Tarn, W. Y. Transportin-SR2 mediates nuclear import of phosphorylated SR proteins. Proc. Natl Acad. Sci. USA 98, 10154–10159 (2001).

4. Amin, E. M. et al. WT1 mutants reveal SRPK1 to be a downstream angiogenesis target by altering VEGF splicing. Cancer Cell 20, 768–780 (2011).

5. Mavrou, A. & Oltean, S. SRPK1 inhibition in prostate cancer: a novel anti-angiogenic treatment through modulation of VEGF alternative splicing. Pharmacol. Res 107, 276–281 (2016).

Cited by 59 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Epigenetic-modifying agents: the potential game changers in the treatment of hematologic malignancies;Critical Reviews in Oncology/Hematology;2024-09

2. Deep PIM kinase substrate profiling reveals new rational cotherapeutic strategies for acute myeloid leukemia;Blood Advances;2024-07-24

3. The splicing factor kinase SRPK1 is a therapeutic target for Peripheral Vascular Disease;2024-04-22

4. Cibler le splicéosome : une nouvelle stratégie thérapeutique pour contrecarrer la résistance à la chimiothérapie dans les cancers du poumon ?;Revue des Maladies Respiratoires;2024-04

5. SRPKIN-1 as an inhibitor against hepatitis B virus blocking the viral particle formation and the early step of the viral infection;Antiviral Research;2023-12