Rational design of a trispecific antibody targeting the HIV-1 Env with elevated anti-viral activity-Reference-Cited by-同舟云学术

Rational design of a trispecific antibody targeting the HIV-1 Env with elevated anti-viral activity

Published:2018-02-28 Issue:1 Volume:9 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Steinhardt James J.,Guenaga Javier,Turner Hannah L.,McKee Krisha,Louder Mark K.^ORCID,O’Dell Sijy,Chiang Chi-I,Lei Lin,Galkin Andrey,Andrianov Alexander K.,A. Doria-Rose Nicole,Bailer Robert T.,Ward Andrew B.,Mascola John R.,Li Yuxing

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/s41467-018-03335-4.pdf

Reference67 articles.

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3. Barouch, D. H. & Deeks, S. G. Immunologic strategies for HIV-1 remission and eradication. Science 345, 169–174 (2014).

4. Burton, D. R. et al. A large array of human monoclonal antibodies to type 1 human immunodeficiency virus from combinatorial libraries of asymptomatic seropositive individuals. Proc. Natl Acad. Sci. USA 88, 10134–10137 (1991).

5. Buchacher, A. et al. Generation of human monoclonal antibodies against HIV-1 proteins; electrofusion and Epstein-Barr virus transformation for peripheral blood lymphocyte immortalization. AIDS Res. Hum. Retroviruses 10, 359–369 (1994).

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