Abstract
AbstractMore people globally depend on the water buffalo than any other domesticated species, and as the most closely related domesticated species to cattle they can provide important insights into the shared evolutionary basis of domestication. Here, we sequence the genomes of 79 water buffalo across seven breeds and compare patterns of between breed selective sweeps with those seen for 294 cattle genomes representing 13 global breeds. The genomic regions under selection between cattle breeds significantly overlap regions linked to stature in human genetic studies, with a disproportionate number of these loci also shown to be under selection between water buffalo breeds. Investigation of potential functional variants in the water buffalo genome identifies a rare example of convergent domestication down to the same mutation having independently occurred and been selected for across domesticated species. Cross-species comparisons of recent selective sweeps can consequently help identify and refine important loci linked to domestication.
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Reference71 articles.
1. Hoffpauir, R. The water buffalo: India’s other bovine. Anthropos 77, 215–238 (1982).
2. Food and Agriculture Organization of the United Nations (FAO). FAOSTAT Statistical Database, http://faostat.fao.org/ (2017).
3. Food and Agriculture Organization of the United Nations. World Watch List for Domestic Animal Diversity. 3rd edn. (Food and Agriculture Organization of the United Nations, Rome, 2000).
4. Kumar, S. et al. Mitochondrial DNA analyses of Indian water buffalo support a distinct genetic origin of river and swamp buffalo. Anim. Genet. 38, 227–232 (2007).
5. Kumar, S., Nagarajan, M., Sandhu, J. S., Kumar, N. & Behl, V. Phylogeography and domestication of Indian river buffalo. BMC Evol. Biol. 7, 186 (2007).
Cited by
46 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献