Aβ34 is a BACE1-derived degradation intermediate associated with amyloid clearance and Alzheimer’s disease progression-Reference-Cited by-同舟云学术

Aβ34 is a BACE1-derived degradation intermediate associated with amyloid clearance and Alzheimer’s disease progression

Published:2019-05-20 Issue:1 Volume:10 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Liebsch Filip^ORCID,Kulic Luka,Teunissen Charlotte^ORCID,Shobo Adeola,Ulku Irem^ORCID,Engelschalt Vivienne,Hancock Mark A.,van der Flier Wiesje M.,Kunach Peter^ORCID,Rosa-Neto Pedro^ORCID,Scheltens Philip^ORCID,Poirier Judes,Saftig Paul,Bateman Randall J.,Breitner John,Hock Christoph,Multhaup Gerhard

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/s41467-019-10152-w.pdf

Reference70 articles.

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3. Wilquet, V. & De Strooper, B. Amyloid-beta precursor protein processing in neurodegeneration. Curr. Opin. Neurobiol. 14, 582–588 (2004).

4. Thinakaran, G. & Koo, E. H. Amyloid precursor protein trafficking, processing, and function. J. Biol. Chem. 283, 29615–29619 (2008).

5. Takami, M. et al. gamma-Secretase: successive tripeptide and tetrapeptide release from the transmembrane domain of beta-carboxyl terminal fragment. J. Neurosci. 29, 13042–13052 (2009).

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