Exploiting interconnected synthetic lethal interactions between PARP inhibition and cancer cell reversible senescence-Reference-Cited by-同舟云学术

Exploiting interconnected synthetic lethal interactions between PARP inhibition and cancer cell reversible senescence

Published:2019-06-11 Issue:1 Volume:10 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Fleury Hubert,Malaquin Nicolas,Tu Véronique^ORCID,Gilbert Sophie,Martinez Aurélie,Olivier Marc-Alexandre^ORCID,Sauriol Alexandre^ORCID,Communal Laudine,Leclerc-Desaulniers Kim,Carmona Euridice,Provencher Diane,Mes-Masson Anne-Marie,Rodier Francis

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/s41467-019-10460-1.pdf

Reference57 articles.

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3. Ledermann, J. et al. Olaparib maintenance therapy in platinum-sensitive relapsed ovarian cancer. New Engl. J. Med. 366, 1382–1392 (2012).

4. Fleury, H. et al. Cumulative defects in DNA repair pathways drive the PARP inhibitor response in high-grade serous epithelial ovarian cancer cell lines. Oncotarget 8, 40152–40168 (2017).

5. Dulaney, C., Marcrom, S., Stanley, J. & Yang, E. S. Poly(ADP-ribose) polymerase activity and inhibition in cancerSemin. Cell Dev. Biol. 63, 144–153 (2017).

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