Estrogen-related receptor γ causes osteoarthritis by upregulating extracellular matrix-degrading enzymes
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Link
http://www.nature.com/articles/s41467-017-01868-8.pdf
Reference54 articles.
1. Hunter, D. J., Schofield, D. & Callander, E. The individual and socioeconomic impact of osteoarthritis. Nat. Rev. Rheumatol. 17, 437–441 (2014).
2. Loeser, R. F. et al. Osteoarthritis: a disease of the joint as an organ. Arthritis Rheum. 64, 1697–1707 (2012).
3. Moon, P. M. & Beirer, F. Novel insights into osteoarthritis joint pathology from studies in mice. Curr. Rheumatol. Rep. 17, 50 (2015).
4. Bian, Q. et al. Osteoarthritis: genetic factors, animal models, mechanisms, and therapies. Front. Biosci. E4, 74–100 (2012).
5. Troeberg, L. & Nagase, H. Proteases involved in cartilage matrix degradation in osteoarthritis. Biochim. Biophys. Acta. 1824, 133–145 (2012).
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