Abstract
AbstractAs the overlap between heart disease and cancer patients increases as cancer-specific mortality is decreasing and the surviving population is aging, it is necessary to identify cancer patients who are at an increased risk of death from heart disease. The purpose of this study is to identify cancer patients at highest risk of fatal heart disease compared to the general population and other cancer patients at risk of death during the study time period. Here we report that 394,849 of the 7,529,481 cancer patients studied died of heart disease. The heart disease-specific mortality rate is 10.61/10,000-person years, and the standardized mortality ratio (SMR) of fatal heart disease is 2.24 (95% CI: 2.23–2.25). Compared to other cancer patients, patients who are older, male, African American, and unmarried are at a greatest risk of fatal heart disease. For almost all cancer survivors, the risk of fatal heart disease increases with time.
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Reference36 articles.
1. Centers or Disease Control and Prevention. Heart Disease. https://www.cdc.gov/heartdisease/facts.htm (2017).
2. Siegel, R. L., Miller, K. D. & Jemal, A. Cancer statistics, 2017. CA: A Cancer J. Clin. 67, 7–30 (2017).
3. Heron, M. & Anderson, R. N. Changes in the leading cause of death: recent patterns in heart disease and cancer mortality. NCHS Data Brief. 1–8 https://www.cdc.gov/nchs/data/databriefs/db254.pdf (2016).
4. Gilchrist, S. C. et al. Cardio-oncology rehabilitation to manage cardiovascular outcomes in cancer patients and survivors: a scientific statement from the American Heart Association. Circulation 139, e997–e1012 (2019).
5. Herrmann, J. et al. Evaluation and management of patients with heart disease and cancer: cardio-oncology. Mayo Clin. Proc. 89, 1287–1306 (2014).
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