Extrapyramidal side effects of antipsychotics are linked to their association kinetics at dopamine D2 receptors
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Link
http://www.nature.com/articles/s41467-017-00716-z.pdf
Reference70 articles.
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3. Meltzer, H. Y. Update on typical and atypical antipsychotic drugs. Annu. Rev. Med. 64, 393–406 (2013).
4. Leucht, S. et al. Second-generation versus first-generation antipsychotic drugs for schizophrenia: a meta-analysis. Lancet 373, 31–41 (2009).
5. Farde, L. et al. Positron emission tomographic analysis of central D1 and D2 dopamine receptor occupancy in patients treated with classical neuroleptics and clozapine. Relation to extrapyramidal side effects. Arch. Gen. Psychiatry 49, 538–544 (1992).
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