Pretrainable geometric graph neural network for antibody affinity maturation
Author:
Funder
Ministry of Science and Technology of the People's Republic of China
Publisher
Springer Science and Business Media LLC
Link
https://www.nature.com/articles/s41467-024-51563-8.pdf
Reference51 articles.
1. Victora, G. D. & Nussenzweig, M. C. Germinal centers. Annu. Rev. Immunol. 40, 413–442 (2022).
2. Gram, H. et al. In vitro selection and affinity maturation of antibodies from a naive combinatorial immunoglobulin library. Proc. Natl. Acad. Sci. USA 89, 3576–3580 (1992).
3. Jackson, J. R., Sathe, G., Rosenberg, M. & Sweet, R. In vitro antibody maturation. improvement of a high affinity, neutralizing antibody against il-1 beta. J. Immunol. 154, 3310–3319 (1995).
4. Li, B. et al. In vitro affinity maturation of a natural human antibody overcomes a barrier to in vivo affinity maturation. In MAbs Vol. 6, 437–445 (Taylor & Francis, 2014).
5. Wang, J. et al. In vitro affinity maturation of antibody against membrane-bound GPCR molecules. Appl. Microbiol. Biotechnol. 103, 7703–7717 (2019).
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