Oxidation of difluorocarbene and subsequent trifluoromethoxylation-Reference-Cited by-同舟云学术

Oxidation of difluorocarbene and subsequent trifluoromethoxylation

Published:2019-11-25 Issue:1 Volume:10 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Yu Jiao,Lin Jin-Hong,Yu Donghai,Du Ruobing,Xiao Ji-Chang

Abstract

AbstractAs a versatile intermediate, difluorocarbene is an electron-deficient transient species, meaning that its oxidation would be challenging. Herein we show that the oxidation of difluorocarbene could occur smoothly to generate carbonyl fluoride. The oxidation process is confirmed by successful trifluoromethoxylation, 18O-trifluoromethoxylation, the observation of AgOCF3 species, and DFT calculations.

Funder

National Natural Science Foundation of China

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/s41467-019-13359-z.pdf

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