A small secreted protein triggers a TLR2/4-dependent inflammatory response during invasive Candida albicans infection
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Link
http://www.nature.com/articles/s41467-019-08950-3.pdf
Reference65 articles.
1. Kullberg, B. J. & Arendrup, M. C. Invasive Candidiasis. N. Engl. J. Med. 373, 1445–1456 (2015).
2. Hofs, S., Mogavero, S. & Hube, B. Interaction of Candida albicans with host cells: virulence factors, host defense, escape strategies, and the microbiota. J. Microbiol. 54, 149–169 (2016).
3. Netea, M. G. et al. Immune sensing of Candida albicans requires cooperative recognition of mannans and glucans by lectin and Toll-like receptors. J. Clin. Invest. 116, 1642–1650 (2006).
4. Jouault, T. et al. Candida albicans phospholipomannan is sensed through toll-like receptors. J. Infect. Dis. 188, 165–172 (2003).
5. Deng, Z. et al. Tyrosine phosphatase SHP-2 mediates C-type lectin receptor-induced activation of the kinase Syk and anti-fungal TH17 responses. Nat. Immunol. 16, 642–652 (2015).
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