Structural basis for GPR40 allosteric agonism and incretin stimulation

Author:

Ho Joseph D.,Chau Betty,Rodgers Logan,Lu Frances,Wilbur Kelly L.,Otto Keith A.,Chen Yanyun,Song Min,Riley Jonathan P.,Yang Hsiu-Chiung,Reynolds Nichole A.,Kahl Steven D.,Lewis Anjana Patel,Groshong Christopher,Madsen Russell E.,Conners Kris,Lineswala Jayana P.,Gheyi Tarun,Saflor Melbert-Brian Decipulo,Lee Matthew R.,Benach Jordi,Baker Kenton A.,Montrose-Rafizadeh Chahrzad,Genin Michael J.,Miller Anne R.,Hamdouchi Chafiq

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Reference45 articles.

1. World Health Organization. Global report on diabetes, http://apps.who.int/iris/bitstream/10665/204871/1/9789241565257_eng.pdf?ua=1 (2016).

2. Centers for Disease Control and Prevention. Diabetes Report Card, http://www.cdc.gov/diabetes/pdfs/library/diabetesreportcard2014.pdf (2014).

3. World Health Organization. World Health Organization: diabetes mellitus fact sheet., http://www.who.int/mediacentre/factsheets/fs138/en/ (2016).

4. Poitout, V. & Lin, D. C. Modulating GPR40: therapeutic promise and potential in diabetes. Drug Discov. Today 18, 1301–1308 (2013).

5. Briscoe, C. P. et al. The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids. J. Biol. Chem. 278, 11303–11311 (2003).

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3