Targeting lonidamine to mitochondria mitigates lung tumorigenesis and brain metastasis
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Link
http://www.nature.com/articles/s41467-019-10042-1.pdf
Reference60 articles.
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3. Goldberg, S. B., Contessa, J. N., Omay, S. B. & Chiang, V. Lung cancer brain metastases. Cancer J. 21, 398–403 (2015).
4. McGranahan, T. & Nagpal, S. A neuro-oncologist’s perspective on management of brain metastases in patients with EGFR mutant non-small cell lung cancer. Curr. Treat. Options Oncol. 18, 22 (2017).
5. Mansi, J. L. et al. A phase II clinical and pharmacokinetic study of Lonidamine in patients with advanced breast cancer. Br. J. Cancer 64, 593–597 (1991).
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