Lysosomal protease deficiency or substrate overload induces an oxidative-stress mediated STAT3-dependent pathway of lysosomal homeostasis-Reference-Cited by-同舟云学术

Lysosomal protease deficiency or substrate overload induces an oxidative-stress mediated STAT3-dependent pathway of lysosomal homeostasis

Published:2018-12 Issue:1 Volume:9 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Martínez-Fábregas Jonathan,Prescott Alan,van Kasteren Sander^ORCID,Pedrioli Deena Leslie,McLean Irwin^ORCID,Moles Anna,Reinheckel Thomas,Poli Valeria^ORCID,Watts Colin^ORCID

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/s41467-018-07741-6.pdf

Reference67 articles.

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3. Settembre, C. et al. A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB. EMBO J. 31, 1095–1108 (2012).

4. Sabatini, D. M. Twenty-five years of mTOR: Uncovering the link from nutrients to growth. Proc. Natl Acad. Sci. USA 114, 11818–11825 (2017).

5. Colbert, J. D., Matthews, S. P., Miller, G. & Watts, C. Diverse regulatory roles for lysosomal proteases in the immune response. Eur. J. Immunol. 39, 2955–2965 (2009).

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