Brain activity patterns in high-throughput electrophysiology screen predict both drug efficacies and side effects
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Link
http://www.nature.com/articles/s41467-017-02404-4.pdf
Reference78 articles.
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3. Bruni, G., Lakhani, P. & Kokel, D. Discovering novel neuroactive drugs through high-throughput behavior-based chemical screening in the zebrafish. Front Pharmacol. 5, 153 (2014).
4. Pardo-Martin, C. et al. High-throughput in vivo vertebrate screening. Nat. Methods 7, 634–636 (2010).
5. Pardo-Martin, C. et al. High-throughput hyperdimensional vertebrate phenotyping. Nat. Commun. 4, 1467 (2013).
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