Corticosteroids inhibit Mycobacterium tuberculosis-induced necrotic host cell death by abrogating mitochondrial membrane permeability transition
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Link
http://www.nature.com/articles/s41467-019-08405-9.pdf
Reference49 articles.
1. WHO. Global tuberculosis report (WHO, Geneva, 2017).
2. Korbee, C. J. et al. Combined chemical genetics and data-driven bioinformatics approach identifies receptor tyrosine kinase inhibitors as host-directed antimicrobials. Nat. Commun. 9, 358 (2018).
3. Kaufmann, S. H. E., Dorhoi, A., Hotchkiss, R. S. & Bartenschlager, R. Host-directed therapies for bacterial and viral infections. Nat. Rev. Drug. Discov. 17, 35–56 (2018).
4. Wallis, R. S. & Hafner, R. Advancing host-directed therapy for tuberculosis. Nat. Rev. Immunol. 15, 255–263 (2015).
5. Guler, R. & Brombacher, F. Host-directed drug therapy for tuberculosis. Nat. Chem. Biol. 11, 748–751 (2015).
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