A plastic aggrecan barrier modulated by peripheral energy state gates metabolic signal access to arcuate neurons
Author:
Funder
Agence Nationale de la Recherche
Publisher
Springer Science and Business Media LLC
Link
https://www.nature.com/articles/s41467-024-50798-9.pdf
Reference45 articles.
1. Jais, A. & Brüning, J. C. Arcuate nucleus-dependent regulation of metabolism-pathways to obesity and diabetes mellitus. Endocr. Rev. 43, 314–328 (2022).
2. Timper, K. & Brüning, J. C. Hypothalamic circuits regulating appetite and energy homeostasis: pathways to obesity. Dis. Model Mech. 10, 679–689 (2017).
3. Ciofi, P. et al. Brain-endocrine interactions: a microvascular route in the mediobasal hypothalamus. Endocrinology 150, 5509–5519 (2009).
4. Olofsson, L. E., Unger, E. K., Cheung, C. C. & Xu, A. W. Modulation of AgRP-neuronal function by SOCS3 as an initiating event in diet-induced hypothalamic leptin resistance. Proc. Natl. Acad. Sci. USA 110, E697–E706 (2013).
5. Morita, S. & Miyata, S. Accessibility of low-molecular-mass molecules to the median eminence and arcuate hypothalamic nucleus of adult mouse. Cell Biochem. Funct. 31, 668–677 (2013).
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