Crystal structure reveals vaccine elicited bactericidal human antibody targeting a conserved epitope on meningococcal fHbp
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Link
http://www.nature.com/articles/s41467-018-02827-7.pdf
Reference64 articles.
1. European Centre for Disease Prevention and Control. Annual Epidemiological Report on Communicable Diseases in Europe 2010. (Stockholm, ECDC, 2010).
2. Sadarangani, M. & Pollard, A. J. Can we control all-cause meningococcal disease in Europe? Clin. Microbiol. Infect. 22 Suppl 5, S103–S112 (2016).
3. Masignani, V. et al. Vaccination against Neisseria meningitidis using three variants of the lipoprotein GNA1870. J. Exp. Med. 197, 789–799 (2003).
4. Fletcher, L. D. et al. Vaccine potential of the Neisseria meningitidis 2086 lipoprotein. Infect. Immun. 72, 2088–2100 (2004).
5. Jiang, H. Q. et al. Broad vaccine coverage predicted for a bivalent recombinant factor H binding protein based vaccine to prevent serogroup B meningococcal disease. Vaccine 28, 6086–6093 (2010).
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