Bik reduces hyperplastic cells by increasing Bak and activating DAPk1 to juxtapose ER and mitochondria
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Link
http://www.nature.com/articles/s41467-017-00975-w.pdf
Reference70 articles.
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3. Shi, Z. O., Fischer, M. J., De Sanctis, G. T., Schuyler, M. R. & Tesfaigzi, Y. IFN-gamma, but not Fas, mediates reduction of allergen-induced mucous cell metaplasia by inducing apoptosis. J. Immunol. 168, 4764–4771 (2002).
4. Pierce, J. et al. Loss of pro-apoptotic Bim promotes accumulation of pulmonary T lymphocytes and enhances allergen-induced goblet cell metaplasia. Am. J. Physiol. Lung. Cell. Mol. Physiol. 291, L862–L870 (2006).
5. Mebratu, Y. A., Dickey, B. F., Evans, C. & Tesfaigzi, Y. The BH3-only protein Bik/Blk/Nbk inhibits nuclear translocation of activated ERK1/2 to mediate IFNgamma-induced cell death. J. Cell. Biol. 183, 429–439 (2008).
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