The exonuclease Xrn1 activates transcription and translation of mRNAs encoding membrane proteins-Reference-Cited by-同舟云学术

The exonuclease Xrn1 activates transcription and translation of mRNAs encoding membrane proteins

Published:2019-03-21 Issue:1 Volume:10 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Blasco-Moreno Bernat,de Campos-Mata Leire^ORCID,Böttcher René,García-Martínez José,Jungfleisch Jennifer,Nedialkova Danny D.,Chattopadhyay Shiladitya,Gas María-Eugenia,Oliva Baldomero^ORCID,Pérez-Ortín José E.^ORCID,Leidel Sebastian A.^ORCID,Choder Mordechai,Díez Juana

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/s41467-019-09199-6.pdf

Reference59 articles.

1. Haimovich, G. et al. Gene expression is circular: factors for mRNA degradation also foster mRNA synthesis. Cell 153, 1000–1011 (2013).

2. Medina, D. A. et al. Cytoplasmic 5’–3’ exonuclease Xrn1p is also a genome-wide transcription factor in yeast. Front. Genet. 5, 1 (2014).

3. Sun, M. et al. Global analysis of eukaryotic mRNA degradation reveals xrn1-dependent buffering of transcript levels. Mol. Cell 52, 52–62 (2013).

4. Pérez-Ortín, J. E., Alepuz, P., Chávez, S. & Choder, M. Eukaryotic mRNA decay: methodologies, pathways, and links to other stages of gene expression. J. Mol. Biol. 425, 3750–3775 (2013).

5. Nagarajan, V. K., Jones, C. I., Newbury, S. F. & Green, P. J. XRN 5’→3’ exoribonucleases: Structure, mechanisms and functions. Biochim. Biophys. Acta 182, 590–603 (2013).

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