Inhibition of glycosphingolipid synthesis with eliglustat in combination with immune checkpoint inhibitors in advanced cancers: preclinical evidence and phase I clinical trial
Author:
Funder
National Natural Science Foundation of China
Publisher
Springer Science and Business Media LLC
Link
https://www.nature.com/articles/s41467-024-51495-3.pdf
Reference53 articles.
1. Hakomori, S. Aberrant glycosylation in tumors and tumor-associated carbohydrate antigens. Adv. cancer Res. 52, 257–331 (1989).
2. Chang, W. W. et al. Expression of Globo H and SSEA3 in breast cancer stem cells and the involvement of fucosyl transferases 1 and 2 in Globo H synthesis. Proc. Natl. Acad. Sci. 105, 11667–11672 (2008).
3. Ho, M. Y., Yu, A. L. & Yu, J. Glycosphingolipid dynamics in human embryonic stem cell and cancer: their characterization and biomedical implications. Glycoconj. J. 34, 765–777 (2017).
4. Lou, Y. W. et al. Stage-specific embryonic antigen-4 as a potential therapeutic target in glioblastoma multiforme and other cancers. Proc. Natl. Acad. Sci. 111, 2482–2487 (2014).
5. Yu, J., Hung, J. T., Wang, S. H., Cheng, J. Y. & Yu, A. L. Targeting glycosphingolipids for cancer immunotherapy. FEBS Lett. 594, 3602–3618 (2020).
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