Promiscuous enzymatic activity-aided multiple-pathway network design for metabolic flux rearrangement in hydroxytyrosol biosynthesis-Reference-Cited by-同舟云学术

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Promiscuous enzymatic activity-aided multiple-pathway network design for metabolic flux rearrangement in hydroxytyrosol biosynthesis

Published:2019-02-27 Issue:1 Volume:10 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Chen Wei,Yao Jun,Meng Jie,Han Wenjing,Tao Yong,Chen Yihua,Guo Yixin,Shi Guizhi,He Yang,Jin Jian-Ming,Tang Shuang-Yan

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/s41467-019-08781-2.pdf

Reference53 articles.

1. Chemler, J. A. & Koffas, M. A. G. Metabolic engineering for plant natural product biosynthesis in microbes. Curr. Opin. Biotechnol. 19, 597–605 (2008).

2. Weber, T. et al. Metabolic engineering of antibiotic factories: new tools for antibiotic production in actinomycetes. Trends Biotechnol. 33, 15–26 (2015).

3. Xiong, D. et al. Improving key enzyme activity in phenylpropanoid pathway with a designed biosensor. Metab. Eng. 40, 115–123 (2017).

4. Inui, T., Tamura, K., Fujii, N., Morishige, T. & Sato, F. Overexpression of Coptis japonica norcoclaurine 6-O-methyltransferase overcomes the rate-limiting step in benzylisoquinoline alkaloid biosynthesis in cultured Eschscholzia californica. Plant Cell Physiol. 48, 252–262 (2007).

5. Tang, S. Y. & Cirino, P. C. Design and application of a mevalonate-responsive regulatory protein. Angew. Chem. Int. Ed. 50, 1084–1086 (2011).

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