Robustly federated learning model for identifying high-risk patients with postoperative gastric cancer recurrence

Author:

Feng Bao,Shi Jiangfeng,Huang Liebin,Yang Zhiqi,Feng Shi-Ting,Li Jianpeng,Chen Qinxian,Xue Huimin,Chen Xiangguang,Wan Cuixia,Hu Qinghui,Cui EnmingORCID,Chen YehangORCID,Long WanshengORCID

Abstract

AbstractThe prediction of patient disease risk via computed tomography (CT) images and artificial intelligence techniques shows great potential. However, training a robust artificial intelligence model typically requires large-scale data support. In practice, the collection of medical data faces obstacles related to privacy protection. Therefore, the present study aims to establish a robust federated learning model to overcome the data island problem and identify high-risk patients with postoperative gastric cancer recurrence in a multicentre, cross-institution setting, thereby enabling robust treatment with significant value. In the present study, we collect data from four independent medical institutions for experimentation. The robust federated learning model algorithm yields area under the receiver operating characteristic curve (AUC) values of 0.710, 0.798, 0.809, and 0.869 across four data centres. Additionally, the effectiveness of the algorithm is evaluated, and both adaptive and common features are identified through analysis.

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry,Multidisciplinary

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