State-level tracking of COVID-19 in the United States

Author:

Unwin H. Juliette T.ORCID,Mishra SwapnilORCID,Bradley Valerie C.,Gandy Axel,Mellan Thomas A.,Coupland Helen,Ish-Horowicz Jonathan,Vollmer Michaela A. C.,Whittaker CharlesORCID,Filippi Sarah L.,Xi Xiaoyue,Monod Mélodie,Ratmann Oliver,Hutchinson Michael,Valka FabianORCID,Zhu Harrison,Hawryluk IwonaORCID,Milton Philip,Ainslie Kylie E. C.,Baguelin Marc,Boonyasiri AdhirathaORCID,Brazeau Nick F.,Cattarino LorenzoORCID,Cucunuba Zulma,Cuomo-Dannenburg GinaORCID,Dorigatti IlariaORCID,Eales Oliver D.,Eaton Jeffrey W.ORCID,van Elsland Sabine L.,FitzJohn Richard G.,Gaythorpe Katy A. M.,Green William,Hinsley Wes,Jeffrey Benjamin,Knock Edward,Laydon Daniel J.ORCID,Lees JohnORCID,Nedjati-Gilani Gemma,Nouvellet Pierre,Okell LucyORCID,Parag Kris V.ORCID,Siveroni IgorORCID,Thompson Hayley A.,Walker Patrick,Walters Caroline E.,Watson Oliver J.ORCID,Whittles Lilith K.,Ghani Azra C.,Ferguson Neil M.ORCID,Riley Steven,Donnelly Christl A.ORCID,Bhatt SamirORCID,Flaxman SethORCID

Abstract

AbstractAs of 1st June 2020, the US Centres for Disease Control and Prevention reported 104,232 confirmed or probable COVID-19-related deaths in the US. This was more than twice the number of deaths reported in the next most severely impacted country. We jointly model the US epidemic at the state-level, using publicly available death data within a Bayesian hierarchical semi-mechanistic framework. For each state, we estimate the number of individuals that have been infected, the number of individuals that are currently infectious and the time-varying reproduction number (the average number of secondary infections caused by an infected person). We use changes in mobility to capture the impact that non-pharmaceutical interventions and other behaviour changes have on the rate of transmission of SARS-CoV-2. We estimate that Rt was only below one in 23 states on 1st June. We also estimate that 3.7% [3.4%–4.0%] of the total population of the US had been infected, with wide variation between states, and approximately 0.01% of the population was infectious. We demonstrate good 3 week model forecasts of deaths with low error and good coverage of our credible intervals.

Funder

Academy of Medical Sciences

Bill and Melinda Gates Foundation

Imperial College Healthcare NHS Trust

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Reference27 articles.

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