Interplay between Notch1 and Notch3 promotes EMT and tumor initiation in squamous cell carcinoma-Reference-Cited by-同舟云学术

Interplay between Notch1 and Notch3 promotes EMT and tumor initiation in squamous cell carcinoma

Published:2017-11-24 Issue:1 Volume:8 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Natsuizaka Mitsuteru,Whelan Kelly A.,Kagawa Shingo,Tanaka Koji,Giroux Veronique,Chandramouleeswaran Prasanna M.,Long Apple,Sahu Varun,Darling Douglas S.,Que Jianwen,Yang Yizeng,Katz Jonathan P.,Wileyto E. Paul,Basu Devraj,Kita Yoshiaki,Natsugoe Shoji,Naganuma Seiji,Klein-Szanto Andres J.,Diehl J. Alan,Bass Adam J.,Wong Kwok-Kin,Rustgi Anil K.,Nakagawa Hiroshi

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/s41467-017-01500-9.pdf

Reference88 articles.

1. Kopan, R. & Ilagan, M. X. The canonical Notch signaling pathway: unfolding the activation mechanism. Cell 137, 216–233 (2009).

2. Blanpain, C., Lowry, W. E., Pasolli, H. A. & Fuchs, E. Canonical notch signaling functions as a commitment switch in the epidermal lineage. Genes Dev. 20, 3022–3035 (2006).

3. Rangarajan, A. et al. Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation. EMBO J. 20, 3427–3436 (2001).

4. Ohashi, S. et al. NOTCH1 and NOTCH3 coordinate esophageal squamous differentiation through a CSL-dependent transcriptional network. Gastroenterology 139, 2113–2123 (2010).

5. Demehri, S., Turkoz, A. & Kopan, R. Epidermal Notch1 loss promotes skin tumorigenesis by impacting the stromal microenvironment. Cancer Cell 16, 55–66 (2009).

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