A requirement for STAG2 in replication fork progression creates a targetable synthetic lethality in cohesin-mutant cancers
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Link
http://www.nature.com/articles/s41467-019-09659-z.pdf
Reference45 articles.
1. Nasmyth, K., Peters, J. M. & Uhlmann, F. Splitting the chromosome: cutting the ties that bind sister chromatids. Science 288, 1379–1385 (2000).
2. Canudas, S. & Smith, S. Differential regulation of telomere and centromere cohesion by the Scc3 homologues SA1 and SA2, respectively, in human cells. J. Cell. Biol. 187, 165–173 (2009).
3. Remeseiro, S. et al. Cohesin-SA1 deficiency drives aneuploidy and tumourigenesis in mice due to impaired replication of telomeres. EMBO J. 31, 2076–2089 (2012).
4. Rao, S. S. P. et al. Cohesin loss eliminates all loop domains. Cell 171, 305–320 (2017).
5. Vian L., et al. The energetics and physiological impact of cohesin extrusion. Cell 173, 1165–1178 (2018).
Cited by 71 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Untangling the loops of STAG2 mutations in myelodysplastic syndrome;Leukemia & Lymphoma;2024-09-12
2. Cohesin mutations in acute myeloid leukemia;Leukemia;2024-09-09
3. Pharmacogenomic discovery of genetically targeted cancer therapies optimized against clinical outcomes;npj Precision Oncology;2024-08-28
4. Adhesin Component Member STAG2 Enhances Cisplatin Tolerance in Colorectal Cancer Cells through the Epithelial-Mesenchymal Transition Pathway;Recent Patents on Anti-Cancer Drug Discovery;2024-07-03
5. Chromatin organization in myelodysplastic syndrome;Experimental Hematology;2024-06
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3