Immunometabolic effects of lactate on humoral immunity in healthy individuals of different ages
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Publisher
Springer Science and Business Media LLC
Link
https://www.nature.com/articles/s41467-024-51207-x.pdf
Reference39 articles.
1. Haas, R. et al. Intermediates of metabolism: from bystanders to signalling molecules. Trends Biochem. Sci. 41, 460–471 (2016).
2. Haas, R. et al. Lactate regulates metabolic and pro-inflammatory circuits in control of T cell migration and effector functions. PLoS Biol. 13, e1002202 (2015).
3. Pucino, V. et al. Lactate buildup at the site of chronic inflammation promotes disease by inducing CD4(+) T cell metabolic rewiring. Cell Metab. 30, 1055–1074 e1058 (2019).
4. Weyand, C. M., Zeisbrich, M. & Goronzy, J. J. Metabolic signatures of T-cells and macrophages in rheumatoid arthritis. Curr. Opin. Immunol. 46, 112–120 (2017).
5. Nichol, A. D. et al. Relative hyperlactatemia and hospital mortality in critically ill patients: a retrospective multi-centre study. Crit. Care 14, R25 (2010).
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