The Pseudomonas aeruginosa lectin LecB binds to the exopolysaccharide Psl and stabilizes the biofilm matrix-Reference-Cited by-同舟云学术

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The Pseudomonas aeruginosa lectin LecB binds to the exopolysaccharide Psl and stabilizes the biofilm matrix

Published:2019-05-16 Issue:1 Volume:10 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Passos da Silva Daniel,Matwichuk Michael L.,Townsend Delaney O.,Reichhardt Courtney,Lamba Doriano,Wozniak Daniel J.,Parsek Matthew R.

Funder

U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases

United States Department of Defense | United States Army | Army Medical Command | U.S. Army Research Institute of Environmental Medicine

Division of Intramural Research, National Institute of Allergy and Infectious Diseases

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/s41467-019-10201-4.pdf

Reference58 articles.

1. Dunne, W. M. Jr. Bacterial adhesion: seen any good biofilms lately? Clin. Microbiol Rev. 15, 155–166 (2002).

2. Rybtke, M., Hultqvist, L. D., Givskov, M. & Tolker-Nielsen, T. Pseudomonas aeruginosa biofilm infections: community structure, antimicrobial tolerance and immune response. J. Mol. Biol. 427, 3628–3645 (2015).

3. Borlee, B. R. et al. Pseudomonas aeruginosa uses a cyclic-di-GMP-regulated adhesin to reinforce the biofilm extracellular matrix. Mol. Microbiol. 75, 827–842 (2010).

4. Byrd, M. S. et al. Genetic and biochemical analyses of the Pseudomonas aeruginosa Psl exopolysaccharide reveal overlapping roles for polysaccharide synthesis enzymes in Psl and LPS production. Mol. Microbiol. 73, 622–638 (2009).

5. Colvin, K. M. et al. The Pel and Psl polysaccharides provide Pseudomonas aeruginosa structural redundancy within the biofilm matrix. Environ. Microbiol 14, 1913–1928 (2012).

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