Corticosteroid suppression of antiviral immunity increases bacterial loads and mucus production in COPD exacerbations-Reference-Cited by-同舟云学术

Corticosteroid suppression of antiviral immunity increases bacterial loads and mucus production in COPD exacerbations

Published:2018-06-08 Issue:1 Volume:9 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Singanayagam Aran,Glanville Nicholas,Girkin Jason L.^ORCID,Ching Yee Man,Marcellini Andrea,Porter James D.,Toussaint Marie,Walton Ross P.,Finney Lydia J.,Aniscenko Julia,Zhu Jie,Trujillo-Torralbo Maria-Belen,Calderazzo Maria Adelaide,Grainge Chris,Loo Su-Ling,Veerati Punnam Chander,Pathinayake Prabuddha S.,Nichol Kristy S.,Reid Andrew T.,James Phillip L.,Solari Roberto,Wark Peter A. B.^ORCID,Knight Darryl A.,Moffatt Miriam F.,Cookson William O.^ORCID,Edwards Michael R.,Mallia Patrick,Bartlett Nathan W.,Johnston Sebastian L.^ORCID

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/s41467-018-04574-1.pdf

Reference60 articles.

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2. Message, S. D. et al. Rhinovirus-induced lower respiratory illness is increased in asthma and related to virus load and Th1/2 cytokine and IL-10 production. Proc. Natl Acad. Sci. USA 105, 13562–13567 (2008).

3. Jackson, D. J. et al. IL-33-dependent type 2 inflammation during rhinovirus-induced asthma exacerbations in vivo. Am. J. Respir. Crit. Care Med. 190, 1373–1382 (2014).

4. Sykes, A. et al. Rhinovirus 16-induced IFN-alpha and IFN-beta are deficient in bronchoalveolar lavage cells in asthmatic patients. J. Allergy Clin. Immunol. 129, 1506–1514 e1506 (2012).

5. Wark, P. A. et al. Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus. J. Exp. Med. 201, 937–947 (2005).

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