The SAM domain of mouse SAMHD1 is critical for its activation and regulation
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Link
http://www.nature.com/articles/s41467-017-02783-8.pdf
Reference42 articles.
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2. Goldstone, D. C. et al. HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase. Nature 480, 379–382 (2011).
3. Descours, B. et al. SAMHD1 restricts HIV-1 reverse transcription in quiescent CD4(+) T-cells. Retrovirology 9, 87 (2012).
4. Bermejo, M. et al. Dasatinib inhibits HIV-1 replication through the interference of SAMHD1 phosphorylation in CD4+T cells. Biochem. Pharmacol. 106, 30–45 (2016).
5. Laguette, N. et al. SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx. Nature 474, 654–657 (2011).
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