ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro-Reference-Cited by-同舟云学术

ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro

Published:2005-03 Issue:7033 Volume:434 Page:648-652
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Stanton Heather,Rogerson Fraser M.,East Charlotte J.,Golub Suzanne B.,Lawlor Kate E.,Meeker Clare T.,Little Christopher B.,Last Karena,Farmer Pamela J.,Campbell Ian K.,Fourie Anne M.,Fosang Amanda J.

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/nature03417.pdf

Reference24 articles.

1. Kuno, K. et al. Molecular cloning of a gene encoding a new type of metalloproteinase-disintegrin family protein with thrombospondin motifs as an inflammation associated gene. J. Biol. Chem. 272, 556–562 (1997)

2. Kuno, K. et al. ADAMTS-1 cleaves a cartilage proteoglycan, aggrecan. FEBS Lett. 478, 241–245 (2000)

3. Rodriguez-Manzaneque, J. C. et al. ADAMTS1 cleaves aggrecan at multiple sites and is differentially inhibited by metalloproteinase inhibitors. Biochem. Biophys. Res. Commun 293, 501–508 (2002)

4. Somerville, R. P. et al. Characterization of ADAMTS-9 and ADAMTS-20 as a distinct ADAMTS subfamily related to Caenorhabditis elegans GON-1. J. Biol. Chem. 278, 9503–9513 (2003)

5. Collins-Racie, L. A. et al. ADAMTS-8 exhibits aggrecanase activity and is expressed in human articular cartilage. Matrix Biol. 23, 219–230 (2004)

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