Mixed models can correct for population structure for genomic regions under selection
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics(clinical),Genetics,Molecular Biology
Link
http://www.nature.com/articles/nrg2813-c1.pdf
Reference6 articles.
1. Price, A. L., Zaitlen, N. A., Reich, D. & Patterson, N. New approaches to population stratification in genome-wide association studies. Nature Rev. Genet. 11, 459–463 (2010).
2. Kang, H. M. et al. Variance component model to account for sample structure in genome-wide association studies. Nature Genet. 42, 348–354 (2010).
3. Price, A. L. et al. Principal components analysis corrects for stratification in genome-wide association studies. Nature Genet. 38, 904–909 (2006).
4. Yang, W.-Y. Y., Novembre, J., Eskin, E. & Halperin, E. A model-based approach for analysis of spatial structure in genetic data. Nature Genet. 44, 725–731 (2012).
5. Sabatti, C. Genome-wide association analysis of metabolic traits in a birth cohort from a founder population. Nature Genet. 41, 35–46 (2008).
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