Regulation of mitotic entry by microcephalin and its overlap with ATR signalling-Reference-Cited by-同舟云学术

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Regulation of mitotic entry by microcephalin and its overlap with ATR signalling

Published:2006-06-18 Issue:7 Volume:8 Page:725-733
ISSN:1465-7392
Container-title:Nature Cell Biology
language:en
Short-container-title:Nat Cell Biol

Author:

Alderton Gemma K.,Galbiati Laura,Griffith Elen,Surinya Katharina H.,Neitzel Heidemarie,Jackson Andrew P.,Jeggo Penny A.,O'Driscoll Mark

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology

Link

http://www.nature.com/articles/ncb1431.pdf

Reference30 articles.

1. Xu, X., Lee, J. & Stern, D. F. Microcephalin is a DNA damage response protein involved in regulation of CHK1 and BRCA1. J. Biol. Chem. 279, 34091–34094 (2004).

2. Lin, S. Y., Rai, R., Li, K., Xu, Z. X. & Elledge, S.J. BRIT1/MCPH1 is a DNA damage responsive protein that regulates the Brca1–Chk1 pathway, implicating checkpoint dysfunction in microcephaly. Proc. Natl Acad. Sci. USA 102, 15105–15109 (2005).

3. Woods, C. G., Bond, J. & Enard, W. Autosomal recessive primary microcephaly (MCPH): a review of clinical, molecular, and evolutionary findings. Am. J. Hum. Genet. 76, 717–728 (2005).

4. Jackson, A. P. et al. Identification of microcephalin, a protein implicated in determining the size of the human brain. Am. J. Hum. Genet. 71, 136–142 (2002).

5. O'Driscoll, M., Ruiz-Perez, V. L., Woods, C. G., Jeggo, P. A. & Goodship, J. A. A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome. Nature Genet. 33, 497–501 (2003).

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