The genetics of the p53 pathway, apoptosis and cancer therapy-Reference-Cited by-同舟云学术

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The genetics of the p53 pathway, apoptosis and cancer therapy

Published:2008-12 Issue:12 Volume:7 Page:979-987
ISSN:1474-1776
Container-title:Nature Reviews Drug Discovery
language:en
Short-container-title:Nat Rev Drug Discov

Author:

Vazquez Alexei,Bond Elisabeth E.,Levine Arnold J.,Bond Gareth L.

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Pharmacology,General Medicine

Link

http://www.nature.com/articles/nrd2656.pdf

Reference84 articles.

1. Levine, A. J. p53, the cellular gatekeeper for growth and division. Cell 88, 323–331 (1997).

2. Riley, T., Sontag, E., Chen, P. & Levine, A. Transcriptional control of human p53-regulated genes. Nature Rev. Mol. Cell Biol. 9, 402–412 (2008).

3. Petitjean, A., Achatz, M. I., Borresen-Dale, A. L., Hainaut, P. & Olivier, M. TP53 mutations in human cancers: functional selection and impact on cancer prognosis and outcomes. Oncogene 26, 2157–2165 (2007).

4. Soussi, T. & Wiman, K. G. Shaping genetic alterations in human cancer: the p53 mutation paradigm. Cancer Cell 12, 303–312 (2007).

5. Iwakuma, T. & Lozano, G. Crippling p53 activities via knock-in mutations in mouse models. Oncogene 26, 2177–2184 (2007).

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