Structural analysis of a novel rabbit monoclonal antibody R53 targeting an epitope in HIV-1 gp120 C4 region critical for receptor and co-receptor binding-Reference-Cited by-同舟云学术

Structural analysis of a novel rabbit monoclonal antibody R53 targeting an epitope in HIV-1 gp120 C4 region critical for receptor and co-receptor binding

Published:2015-01-01 Issue:1 Volume:4 Page:1-8
ISSN:2222-1751
Container-title:Emerging Microbes & Infections
language:en
Short-container-title:Emerging Microbes & Infections

Author:

Pan Ruimin¹,Chen Yuxin²,Vaine Michael²,Hu Guangnan²,Wang Shixia²,Lu Shan²,Kong Xiang-Peng¹

Affiliation:

1. Departments of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY 10016, USA

2. Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA

Publisher

Informa UK Limited

Subject

Virology,Infectious Diseases,Drug Discovery,General Medicine,Immunology,Microbiology,Parasitology,Epidemiology

Link

http://www.nature.com/articles/emi201544.pdf

Reference42 articles.

1. HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites

2. Structure and immune recognition of trimeric pre-fusion HIV-1 Env

3. Conserved structural elements in the V3 crown of HIV-1 gp120

4. Thermodynamic Signatures of the Antigen Binding Site of mAb 447–52D Targeting the Third Variable Region of HIV-1 gp120

5. Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2

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