Targeting TGFβ-activated kinase-1 activation in microglia reduces CAR T immune effector cell-associated neurotoxicity syndrome-Reference-Cited by-同舟云学术

Targeting TGFβ-activated kinase-1 activation in microglia reduces CAR T immune effector cell-associated neurotoxicity syndrome

Published:2024-05-13 Issue:8 Volume:5 Page:1227-1249
ISSN:2662-1347
Container-title:Nature Cancer
language:en
Short-container-title:Nat Cancer

Author:

Vinnakota Janaki Manoja,Biavasco Francesca,Schwabenland Marius^ORCID,Chhatbar Chintan,Adams Rachael C.,Erny Daniel^ORCID,Duquesne Sandra,El Khawanky Nadia,Schmidt Dominik^ORCID,Fetsch Viktor,Zähringer Alexander,Salié Henrike^ORCID,Athanassopoulos Dimitrios,Braun Lukas M.^ORCID,Javorniczky Nora R.,Ho Jenny N. H. G.,Kierdorf Katrin^ORCID,Marks Reinhard,Wäsch Ralph^ORCID,Simonetta Federico,Andrieux Geoffroy^ORCID,Pfeifer Dietmar,Monaco Gianni,Capitini Christian^ORCID,Fry Terry J.^ORCID,Blank Thomas^ORCID,Blazar Bruce R.^ORCID,Wagner Eva^ORCID,Theobald Matthias,Sommer Clemens,Stelljes Matthias,Reicherts Christian,Jeibmann Astrid,Schittenhelm Jens,Monoranu Camelia-Maria,Rosenwald Andreas,Kortüm Martin^ORCID,Rasche Leo^ORCID,Einsele Hermann^ORCID,Meyer Philipp T.,Brumberg Joachim,Völkl Simon,Mackensen Andreas,Coras Roland,von Bergwelt-Baildon Michael,Albert Nathalie L.,Bartos Laura M.,Brendel Matthias,Holzgreve Adrien^ORCID,Mack Matthias^ORCID,Boerries Melanie^ORCID,Mackall Crystal L.^ORCID,Duyster Justus,Henneke Philipp,Priller Josef,Köhler Natalie^ORCID,Strübing Felix^ORCID,Bengsch Bertram^ORCID,Ruella Marco^ORCID,Subklewe Marion^ORCID,von Baumgarten Louisa^ORCID,Gill Saar,Prinz Marco^ORCID,Zeiser Robert^ORCID

Publisher

Springer Science and Business Media LLC

Link

https://www.nature.com/articles/s43018-024-00764-7.pdf

Reference78 articles.

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2. Maude, S. et al. Tisagenlecleucel in children and young adults with B-cell lymphoblastic leukemia. N. Engl. J. Med. 378, 439–448 (2018).

3. Neelapu, S. S. et al. Axicabtagene ciloleucel CAR T-cell therapy in refractory large B-cell lymphoma. N. Engl. J. Med. 377, 2531–2544 (2017).

4. Belin, C. et al. Description of neurotoxicity in a series of patients treated with CAR T-cell therapy. Sci. Rep. 10, 18997 (2020).

5. Sterner, R. C. & Sterner, R. M. Immune effector cell associated neurotoxicity syndrome in chimeric antigen receptor-T cell therapy. Front. Immunol. 13, 879608 (2022).

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